Respiratory

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Nerandomilast is an investigational oral, preferential inhibitor of phosphodiesterase 4B that has shown promise in IPF and PPF. | Image credit: Елена Бутусова - stock.adobe.com

Nerandomilast Improves Lung Function in Progressive Pulmonary Fibrosis: FIBRONEER-ILD

By Rose McNulty

February 13th 2025

Patients with progressive pulmonary fibrosis who received nerandomilast showed improved forced vital capacity from baseline at 52 weeks in the phase 3 FIBRONEER-ILD trial.

Sanofi | Image credit: Eagle - stock.adobe.com

Combination Influenza and COVID-19 Vaccine Candidates Granted Fast Track Designation

By Pearl Steinzor

December 16th 2024

Group of diverse kids | Image Credit: © EKKAPON-stock.adobe.com

Ambient Toxins Linked to Disabilities in Minority Schoolchildren

By Maggie L. Shaw

December 10th 2024

RSV vaccine | Image credit: Pawel - atock.adobe.com

Nirsevimab Protected Infants, Children From Severe RSV in 2023–2024 Season

By Pearl Steinzor

December 6th 2024

Doctor with an image of lungs | Image credit: lungs_PRASANNAPIX

Key Flu and RSV Recommendations for the 2024-2025 Respiratory Virus Season

By Lauren Biscaldi, MS

November 26th 2024

Continuing Medical Education

April 25th 2025

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory

More News

The Potential of NLP to Diagnose Childhood Asthma Earlier, Improve Future Outcomes

April 25th 2019

The Potential of NLP to Diagnose Childhood Asthma Earlier, Improve Future Outcomes

Allison Inserro

Using a form of artificial intelligence called natural language processing (NLP) to mine information in electronic health records (EHRs) can uncover early cases of childhood asthma more quickly, reducing the long-term morbidity of this chronic disease, improve current care, and streamline and advance new therapeutic discoveries.

CRISPR Gene Editing Technology Successfully Treated Lethal Lung Disease in Animal Models

April 20th 2019

CRISPR Gene Editing Technology Successfully Treated Lethal Lung Disease in Animal Models

Samantha DiGrande

In a proof-of-concept study recently published in Science Translational Medicine, researchers from Penn Medicine and the Children’s Hospital of Philadelphia were able to edit out a lethal lung disease using CRISPR in utero mice models.

Bill Seeks to Ban Online Sales of e-Cigarettes, Raise Age to Buy Tobacco to 21

April 17th 2019

Bill Seeks to Ban Online Sales of e-Cigarettes, Raise Age to Buy Tobacco to 21

Allison Inserro

Two Democratic members of Congress introduced a bill this week aimed at reversing the increase in vaping among children and teenagers by raising the minimum purchasing age for all tobacco products to 21 years old, among other things.

C-Section Births Associated With Delay in Microbiota Development, Respiratory Infections

April 13th 2019

C-Section Births Associated With Delay in Microbiota Development, Respiratory Infections

Samantha DiGrande

During the European Congress of Clinical Microbiology & Infectious Disease (ECCMID), being held in Amsterdam, the Netherlands, April 13-16, researchers are presenting findings that suggests the mode of delivery influences the development of gut microbiota in infants, regardless of a mother’s use of antibiotics, which could then affect infants’ respiratory health during his or her first year.

Traffic-Related Pollution Linked to New Pediatric Asthma Cases Every Year

April 11th 2019

Traffic-Related Pollution Linked to New Pediatric Asthma Cases Every Year

Allison Inserro

The United States ranks highly in a global study examining traffic-related pollution and new cases of childhood asthma, and the authors suggest that pollution guidelines may need to be re-evaluated, since most affected children live in areas where pollution falls within current limits.

Can Sugar Inhalation Treat Respiratory Illness?

April 6th 2019

Can Sugar Inhalation Treat Respiratory Illness?

Samantha DiGrande

A recent study conducted in mice found that the ability of cells to use glucose can actually help to regulate the immune system during lung inflammation.

Type of Fire Affects Immune System Differently, Study Finds

April 6th 2019

Type of Fire Affects Immune System Differently, Study Finds

Allison Inserro

There may be a difference between controlled burns and wildfires on one’s immune system.

February 24th 2019

Improving Outcomes for Children With Persistent Asthma

Wallace Stephens

Two abstracts presented Saturday at The American Academy of Allergy, Asthma & Immunology 2019 Annual Meeting, held February 22-25 in San Francisco, California, discussed how formulary switching can affect outcomes for patients with severe persistent asthma, as well as how improving outcomes may be associated with increased quality measures.

Investigating Manual Therapy as a Treatment for COPD

February 14th 2019

Investigating Manual Therapy as a Treatment for COPD

Wallace Stephens

There is not enough evidence that manual therapy—a clinical approach of using skilled, physical, hands-on procedures to improve function, lessen pain, and facilitate movement—can successfully be used to treat chronic obstructive pulmonary disease (COPD).

High-Dose Liquid Birch Pollen Extract Safely Reduced Symptoms in Adults With Pollen Allergies, Trial Results Show

December 29th 2018

High-Dose Liquid Birch Pollen Extract Safely Reduced Symptoms in Adults With Pollen Allergies, Trial Results Show

Patients with allergies to birch pollen who took drops of birch pollen extract under the tongue for 3 to 6 months were able to reduce their symptoms and improve their quality of life.

CDC Issues Alert on Resurgence of Progressive Massive Fibrosis in Coal Miners

December 27th 2018

CDC Issues Alert on Resurgence of Progressive Massive Fibrosis in Coal Miners

CDC noted a rise in black lung disease, a potentially lethal disease, with a new report of a cluster of 60 cases identified in former and current coal miners at a single eastern Kentucky radiologist’s practice from January 2015 to August 2016.

Focusing on High-Risk Patients With TB May Help Eliminate the Disease in US

December 22nd 2018

Focusing on High-Risk Patients With TB May Help Eliminate the Disease in US

Focusing on patients with latent tuberculosis (TB) infection who are at high risk of developing active TB may be key to eliminating the disease in the United States; however, a study found that physicians are not systematically identifying risk levels for patients with latent TB.

Preventing Wheezing/Asthma Attacks in Preschool Children

December 21st 2018

Preventing Wheezing/Asthma Attacks in Preschool Children

Researchers found no evidence that initiation of inhaled corticosteroids or leukotriene receptor antagonist therapy is associated with fewer wheezing/asthma attacks than therapy with a short-acting ß-agonist alone in preschool children with recurrent wheezing/asthma.

Assessing Physician Awareness, Management of Coexisting Asthma and Allergic Rhinitis in Asia-Pacific Region

December 21st 2018

Assessing Physician Awareness, Management of Coexisting Asthma and Allergic Rhinitis in Asia-Pacific Region

While there is widespread acceptance of the coexistent asthma–AR and the associated burden among physicians, a new study highlighted the need for increased healthcare practitioner communication and awareness to improve the appropriate treatment and management of these 2 coexistent conditions.

Nontuberculous Mycobacterial Lung Disease Doubled the Risk of Death in a Managed Care Population

December 14th 2018

Nontuberculous Mycobacterial Lung Disease Doubled the Risk of Death in a Managed Care Population

A new study examining the public health burden of nontuberculous mycobacterial lung disease in the United States has found that all-cause mortality, adjusted for other factors, more than doubled with NTMLD compared with an age- and sex-matched control group.

Duration of Disturbed Breathing During Sleep Predicts Mortality

December 13th 2018

Duration of Disturbed Breathing During Sleep Predicts Mortality

How long a person with obstructive sleep apnea (OSA) stops breathing may be a better predictor of mortality risk from OSA in both women and men than the number of times they stop breathing, a new study published in the American Journal of Respiratory and Critical Care Medicine concludes.

Promising Testing Tool Can Provide Accurate Diagnosis of Lower Respiratory Infections

December 8th 2018

Promising Testing Tool Can Provide Accurate Diagnosis of Lower Respiratory Infections

A next generation DNA sequencing study offers a streamlined protocol that integrates the genomic portrait of pathogen, microbiome, and host transcriptome for a more accurate diagnosis of lower respiratory tract infections.

Baseline Factors Can Identify Positive Response to Benralizumab in Severe Asthma

December 7th 2018

Baseline Factors Can Identify Positive Response to Benralizumab in Severe Asthma

A study published in the European Respiratory Journal suggests that in addition to elevated blood eosinophil counts, baseline clinical factors can help identify patients who would potentially be responsive to benralizumab (Fasenra), among patients with severe, uncontrolled asthma with eosinophilic inflammation.

Obesity a Major Preventable Risk Factor for Asthma in Children

November 30th 2018

Obesity a Major Preventable Risk Factor for Asthma in Children

A new study in Pediatrics concludes that 23%-27% of new asthma cases in children with obesity is directly attributable to obesity, and without overweight and obesity as a factor there would be 10% fewer cases of pediatric asthma in the United States.

Nurse-Led Cognitive Behavioral Therapy Cost-Effective in COPD

November 27th 2018

Nurse-Led Cognitive Behavioral Therapy Cost-Effective in COPD

Cognitive behavioral therapy delivered by respiratory nurses can reduce anxiety and is cost-effective in patients with chronic obstructive pulmonary disease (COPD).

ICER Report Estimates 50% Discount for Asthma Biologics to Be Cost-Effective

November 24th 2018

ICER Report Estimates 50% Discount for Asthma Biologics to Be Cost-Effective

There are 5 FDA-approved monoclonal antibody treatments that affect the pathways involved in either the allergic or type 2 inflammatory phenotypes of asthma, and these 5 drugs are the focus of a new report from the Institute for Clinical and Economic Review (ICER).

Endothelial Microparticles as Predictive Biomarkers for COPD Exacerbations

November 20th 2018

Endothelial Microparticles as Predictive Biomarkers for COPD Exacerbations

A new study, published in the International Journal of COPD, concludes that the increase in endothelial microparticles and various microparticles in the systemic circulation that accompanies chronic obstructive pulmonary disease (COPD) can lead to disease exacerbation and could be used as early biomarkers on disease progression.

FDA Takes Steps to Prevent Access to Flavored Tobacco Products, Ban Menthol Cigarettes

November 16th 2018

FDA Takes Steps to Prevent Access to Flavored Tobacco Products, Ban Menthol Cigarettes

The FDA today announced new actions aimed at reversing the increasing trend of youth nicotine use and combating youth access to e-cigarettes. Though the agency stopped short of an expected ban on flavored e-cigarettes, it will move to outlaw menthol cigarettes and flavored cigars, 2 products that disproportionately harm African Americans.

Most Patients With CF May Get Insufficient Antibiotics to Fight Lung Infections

November 14th 2018

Most Patients With CF May Get Insufficient Antibiotics to Fight Lung Infections

A new study by Children’s National Health System researchers suggests that the majority of patients with cystic fibrosis (CF) may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria causing pulmonary exacerbations.

Hoping to Fend Off FDA, Juul to Stop Selling Certain e-Cig Flavors, For Now

November 14th 2018

Hoping to Fend Off FDA, Juul to Stop Selling Certain e-Cig Flavors, For Now

Allison Inserro

Facing the threat of impending US regulatory action, Juul Labs said Tuesday it would voluntarily stop selling certain flavors of its flavored e-cigarettes in retail stores on a temporary basis, but would continue to sell them online, and plans to improve its age-verification system.

ALA, ATS Seek Increase in Lung Cancer Screenings With New Healthcare Guide

November 13th 2018

ALA, ATS Seek Increase in Lung Cancer Screenings With New Healthcare Guide

Allison Inserro

An estimated 25,000 Americans who are at high risk for developing lung cancer would be saved annually through low-dose computed tomography (CT) scans, but only 5% of people who qualify are screened. In an effort to increase the number of people getting screened, the American Lung Association (ALA) and the American Thoracic Society (ATS) unveiled a Lung Cancer Screening Implementation Guide during Lung Cancer Awareness Month.

Secondhand Exposure to Electronic Nicotine Delivery Systems Linked to Asthma Symptoms in Youth

November 11th 2018

Secondhand Exposure to Electronic Nicotine Delivery Systems Linked to Asthma Symptoms in Youth

A new study in Chest has identified a correlation between electronic nicotine delivery systems (ENDS) and asthma symptoms in youth. The association was independent of cigarette smoking and ENDS use and exposure to secondhand cigarette smoke.

Prevalence of Showerhead Bacteria Correlates With Prevalence of NTM Lung Infections

November 6th 2018

Prevalence of Showerhead Bacteria Correlates With Prevalence of NTM Lung Infections

A study published in the journal mBio has found a correlation between regions where mycobacteria are most prevalent in showerhead biofilm and regions where nontuberous mycobacterial (NTM) lung infections are the most prevalent, providing more evidence about the important role played by showerheads in transmission of NTM lung infections in the United States and Europe.

Oxygenation Strategies May Not Be Most Effective for Treating Acute Hypoxemic Respiratory Failure, Study Finds

November 4th 2018

Oxygenation Strategies May Not Be Most Effective for Treating Acute Hypoxemic Respiratory Failure, Study Finds

Alison Rodriguez

A study that examined mortality among immunocompromised patients with acute hypoxemic respiratory failure found that high-flow oxygen therapy did not significantly decrease 28-day mortality compared with standard oxygen therapy.

5 Updates on Lung Cancer Mortality, Risk, and Treatment

November 2nd 2018

5 Updates on Lung Cancer Mortality, Risk, and Treatment

Jaime Rosenberg

November marks Lung Cancer Awareness Month, which seeks to put a spotlight on the leading cause of cancer death. Here are 5 things to know about the disease.

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