Respiratory

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Nerandomilast is an investigational oral, preferential inhibitor of phosphodiesterase 4B that has shown promise in IPF and PPF. | Image credit: Елена Бутусова - stock.adobe.com

Nerandomilast Improves Lung Function in Progressive Pulmonary Fibrosis: FIBRONEER-ILD

By Rose McNulty

February 13th 2025

Patients with progressive pulmonary fibrosis who received nerandomilast showed improved forced vital capacity from baseline at 52 weeks in the phase 3 FIBRONEER-ILD trial.

Sanofi | Image credit: Eagle - stock.adobe.com

Combination Influenza and COVID-19 Vaccine Candidates Granted Fast Track Designation

By Pearl Steinzor

December 16th 2024

Group of diverse kids | Image Credit: © EKKAPON-stock.adobe.com

Ambient Toxins Linked to Disabilities in Minority Schoolchildren

By Maggie L. Shaw

December 10th 2024

RSV vaccine | Image credit: Pawel - atock.adobe.com

Nirsevimab Protected Infants, Children From Severe RSV in 2023–2024 Season

By Pearl Steinzor

December 6th 2024

Doctor with an image of lungs | Image credit: lungs_PRASANNAPIX

Key Flu and RSV Recommendations for the 2024-2025 Respiratory Virus Season

By Lauren Biscaldi, MS

November 26th 2024

Continuing Medical Education

April 25th 2025

Managing Patients With COPD: Evidence-Based Care and Optimizing Value of New and Emerging Targeted Therapies

1.0 Credit / Immunology, Pulmonology/Respiratory

More News

COVID-19 Roundup: 21 Passengers on Calif. Cruise Ship Test Positive

March 7th 2020

COVID-19 Roundup: 21 Passengers on Calif. Cruise Ship Test Positive

Twenty-one people aboard a cruise ship carrying more than 3500 people off the California coast tested positive for the new coronavirus, but only 46 people overall have been tested, and federal officials are trying to bring the ship to a non-commercial port. COVID-19 (which stands for coronavirus disease 2019) passed a global milestone; SARS-CoV-2, the virus that causes the disease, has infected more than 100,000 worldwide.

This Week in Managed Care: March 6, 2020

March 6th 2020

This Week in Managed Care: March 6, 2020

This week, the top stories in managed care included a study finding key drug prices are soaring; Congress providing funds for coronavirus; alcohol-related deaths rising.

FDA Steps Up Warning for Montelukast for Risk of Mental Health Side Effects

March 5th 2020

FDA Steps Up Warning for Montelukast for Risk of Mental Health Side Effects

The FDA now requires a boxed warning for montelukast (Singulair) due to the risk of neuropsychiatric events associated with the drug.

Effects of AE-ILD in Patients With Idiopathic Inflammatory Myopathy

March 4th 2020

Effects of AE-ILD in Patients With Idiopathic Inflammatory Myopathy

Treatment regimens of steroids and disease-modifying antirheumatic drugs were effective in reducing the short-term death rate among patients with acute exacerbation of interstitial lung disease (AE-ILD), a complication of idiopathic inflammatory myopathy.

Wash. State Sees First US Coronavirus Death and First Healthcare Worker Infected

March 1st 2020

Wash. State Sees First US Coronavirus Death and First Healthcare Worker Infected

Allison Inserro

A man in his 50s in Washington state with underlying health conditions became the first fatality from the coronavirus in the United States, and a healthcare worker and a resident from a nursing home in the state are hospitalized, the CDC said Saturday. It is the first reported case in a healthcare worker, the CDC said.

CDC Warns That COVID-19 Is Likely Headed Toward Pandemic Stage, Could Affect US Schools, Businesses

February 26th 2020

CDC Warns That COVID-19 Is Likely Headed Toward Pandemic Stage, Could Affect US Schools, Businesses

Allison Inserro

It’s not a question of if coronavirus becomes a worldwide pandemic, but when, the CDC said Tuesday.

Frequent Exposure to Cleaning Products in Early Childhood Linked With Asthma, Wheezing

February 22nd 2020

Frequent Exposure to Cleaning Products in Early Childhood Linked With Asthma, Wheezing

By age 3, children involved in the survey developed wheeze, atopy, or asthma—possibly linked to their parents’ use of common household cleaning products.

Researchers Describe Possibilities for Improving Lung Cancer Screening in Smokers

February 17th 2020

Researchers Describe Possibilities for Improving Lung Cancer Screening in Smokers

Alison Rodriguez

A decision aid delivered through tobacco quitlines may improve informed decision making about lung cancer screening, according to study findings.

AJMC® in the Press, February 14, 2020

February 14th 2020

AJMC® in the Press, February 14, 2020

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Knowledge About Effective Therapies for Interstitial Lung Disease Lacking, Review Says

February 14th 2020

Knowledge About Effective Therapies for Interstitial Lung Disease Lacking, Review Says

Interstitial lung disease requires a multidisciplinary clinical approach, though little is known about effective therapeutic treatments.

February 12th 2020

Preventive Drug Lists as Tools for Managing Asthma Medication Costs

Melissa B. Gilkey, PhD Lauren A. Cripps, MA Rachel S. Gruver, MPH Deidre V. Washington, PhD Alison A. Galbraith, MD, MPH

Findings of this qualitative interview study suggest promise, but also challenges, with regard to using preventive drug lists to help families manage asthma medication costs.

Experts Warn of Child Flu Outbreak in Detention Centers

February 5th 2020

Experts Warn of Child Flu Outbreak in Detention Centers

Infectious disease experts at the University of Maryland School of Medicine recently warned there is an urgent need for the administration of influenza vaccines among detainees at the southern border.

Lung Microbiome Found to Predict Outcomes in Critically Ill Patients

January 29th 2020

Lung Microbiome Found to Predict Outcomes in Critically Ill Patients

Matthew Gavidia

Key features of the lung microbiome (bacterial burden, enrichment with gut-associated bacteria) were found to predict outcomes in critically ill patients, representing a potential therapeutic target for the prevention and treatment of acute respiratory failure, according to study findings.

HHS Secretary Azar Issues Updates on Novel Coronavirus

January 29th 2020

HHS Secretary Azar Issues Updates on Novel Coronavirus

In a press conference, HHS secretary Alex Azar provided updates on the US government’s response to the 2019 novel coronavirus. He was joined by the director of the CDC, Robert Redfield, MD; the director of CDC’s National Center for Immunization and Respiratory Diseases, Nancy Messonnier, MD; and the director of the National Institutes of Health’s National Institute of Allergy and Infectious Diseases, Anthony Fauci, MD.

Surgeon General Releases New Report on Smoking Cessation

January 24th 2020

Surgeon General Releases New Report on Smoking Cessation

The US Surgeon General, Jerome M. Adams, MD, MPH, has released the first report since 1990 that focuses solely on smoking cessation in America. Smoking accounts for the deaths of half a million Americans each year and is the leading cause of preventable disease, disability, and death in the country.

What We're Reading: Healthcare Issues to Watch; e-Cig Flavor Ban; Google AI and Breast Cancer

January 2nd 2020

What We're Reading: Healthcare Issues to Watch; e-Cig Flavor Ban; Google AI and Breast Cancer

Five issues in healthcare were spotlighted as key developments to watch; FDA to ban all e-cig vape flavors except for menthol and tobacco; Google AI system shown to improve detection of breast cancer through mammograms.

Chemical Found in e-Cigarette Fluid Linked to Vaping-Related Respiratory Failure of Teen

November 13th 2019

Chemical Found in e-Cigarette Fluid Linked to Vaping-Related Respiratory Failure of Teen

Matthew Gavidia

The fluid in e-cigarettes were associated with the near fatal respiratory failure of a teenage boy who was found to have an exaggerated immune response to one of its chemicals while vaping, according to a report published this week by doctors.

Dr Lisa Lancaster on Evolving Treatments in Pulmonology

November 6th 2019

Dr Lisa Lancaster on Evolving Treatments in Pulmonology

New trials are looking at what could be the next therapy or one that layers on top of present therapies to treat lung diseases, said Lisa Lancaster, MD, assistant professor of medicine at Vanderbilt Health.

Clofazimine-Containing Regimen Shown to Safely, Effectively Treat Rapidly Growing Mycobacteria Infections

November 6th 2019

Clofazimine-Containing Regimen Shown to Safely, Effectively Treat Rapidly Growing Mycobacteria Infections

Matthew Gavidia

A clofazimine-containing regimen was found to be well tolerated and potentially effective in patients with rapidly growing mycobacteria infection, especially nonpulmonary and non–Mycobacterium abscessus complex infections, according to retrospective cohort study findings.

Outcomes-Based Contract Between Highmark, AstraZeneca Reveals Positive Results for Patients With Asthma and COPD

November 2nd 2019

Outcomes-Based Contract Between Highmark, AstraZeneca Reveals Positive Results for Patients With Asthma and COPD

Matthew Gavidia

Highmark announced this week that its outcomes-based contract with AstraZeneca for the respiratory combination medication of budesonide/formoterol (Symbicort) revealed positive results in improving outcomes for those with asthma and chronic obstructive pulmonary disease (COPD).

Top 5 AJMC® Articles of October 2019

November 1st 2019

Top 5 AJMC® Articles of October 2019

Here are the top 5 articles for the month of October.

Researchers Explore Costs of Switching to Environmentally Friendly Inhalers for Asthma

October 31st 2019

Researchers Explore Costs of Switching to Environmentally Friendly Inhalers for Asthma

Christina Mattina

Reducing the use of metered-dose inhalers for asthma could shrink the carbon footprint while achieving cost savings if less expensive brands of dry powder inhalers are used, according to new research findings.

This Week in Managed Care: October 25, 2019

October 25th 2019

This Week in Managed Care: October 25, 2019

This week, the top managed care news included the average Affordable Care Act premiums falling 4%; the FDA approving a triple combination treatment for cystic fibrosis; House Republicans releasing part 1 of their healthcare plan.

Dr Lisa Lancaster Discusses the Overlap of Sleep Apnea and Lung Diseases

October 22nd 2019

Dr Lisa Lancaster Discusses the Overlap of Sleep Apnea and Lung Diseases

Lisa Lancaster, MD, assistant professor of medicine at Vanderbilt Health, discusses how sleep apnea is a comorbidity for other lung diseases, such as chronic obstructive pulmonary disease (COPD) and interstitial lung disease.

FDA Approves Novel Triple Combination Therapy for Cystic Fibrosis

October 22nd 2019

FDA Approves Novel Triple Combination Therapy for Cystic Fibrosis

Matthew Gavidia

The FDA approved the triple combination of elexacaftor, ivacaftor, and tezacaftor, to be sold under the name Trikafta, as a novel treatment among patients with the most common cystic fibrosis mutation.

Water Treatment Strategies Vary in Effectiveness Against Bacterial Species Causing Respiratory Infections

October 17th 2019

Water Treatment Strategies Vary in Effectiveness Against Bacterial Species Causing Respiratory Infections

Christina Mattina

Several species of bacteria that can transmit respiratory infections have varying levels of response to the disinfecting agents used in municipal water treatment systems, with no one water disinfection strategy achieving complete microbial control, according to new findings.

High Levels of Chronic Stress, High Blood Pressure Linked in African Americans

October 16th 2019

High Levels of Chronic Stress, High Blood Pressure Linked in African Americans

Matthew Gavidia

African Americans who report high levels of chronic stress were shown to be at a heightened risk of developing high blood pressure, or hypertension, with specific stressors such as discrimination and socioeconomic status serving as possible catalysts, according to study findings.

Exposure to e-Cigarette Smoke Associated With Lung Cancer in Mice

October 9th 2019

Exposure to e-Cigarette Smoke Associated With Lung Cancer in Mice

Matthew Gavidia

Long term e-cigarette impact on humans remains unknown, although studies on mice suggest potentially harmful consequences for users.

Research Identifies Asthma Endotypes Suggesting Different Treatment Strategies

October 9th 2019

Research Identifies Asthma Endotypes Suggesting Different Treatment Strategies

Christina Mattina

An in-press study detailed the characteristics of 4 asthma endotypes and their association with asthma-related healthcare outcomes and responsiveness to treatment.

Three-in-One Inhaler Found to Improve Lung Function, Reduce Asthma Attacks in 2 Phase 3 Trials

October 3rd 2019

Three-in-One Inhaler Found to Improve Lung Function, Reduce Asthma Attacks in 2 Phase 3 Trials

Matthew Gavidia

Research presented at the European Respiratory Society Conference 2019 details the novel use of a single inhaler combining 3 therapies, as opposed to 2, in 2 clinical studies on patients with severe asthma.

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