Oncology

Latest News

NSCLC | Image: Lung Cancer Foundation of America

Zongertinib Shows Durable Responses With No Interstitial Lung Disease in HER2-Mutated Advanced NSCLC

By Mary Caffrey
Brooke McCormick

April 28th 2025

Results could give patients with HER2-mutated non–small cell lung cancer (NSCLC) an oral therapy option.

Considering the life-threatening risk of TLS, the researchers underscored the importance of identifying patients at particular risk of the complication. | Image credit: mi_viri - stock.adobe.com

Optimized Strategies Needed for TLS Prevention, Intervention in SCLC

By AJMC Contributor

April 23rd 2025

Diabetes monitoring | Image credit: abidika - stock.adobe.com

New-Onset Type 2 Diabetes Linked to Higher Cancer Risk

By Pearl Steinzor

April 23rd 2025

Vitamin D | Image credit: Galina Zhigalova - stock.adobe.com

Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health

By Pearl Steinzor

April 23rd 2025

The study highlighted symptom patterns in the short-term preceding ED visits and unplanned hospitalizations using a previously validated natural language processing a pipeline. | Image credit: Tyler Olson - stock.adobe.com

Symptom Documentation Differences in Acute Cancer Care Suggest Sociodemographic Disparities

By Rose McNulty

April 22nd 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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July 13th 2015

Palliative Care in Cancer: When Does the Discussion Begin?

Surabhi Dangi-Garimella, PhD

During the Oncology Stakeholder's Summit 2015 hosted by AJMC, healthcare experts discuss the value of introducing palliative and end-of-life care discussions early in oncology care.

July 13th 2015

Will Specialty Oncology Products Follow the Sovaldi Way?

Surabhi Dangi-Garimella, PhD

The American Journal of Managed Care invited healthcare experts to discuss the challenges associated with managing and paying for newer and more expensive agents in oncology, during the Oncology Stakeholders Summit.

July 11th 2015

This Week in Managed Care: July 11, 2015

The top story of the week was Aetna's purchase of Humana, which signals a growth in government managed care. In addition, the 340B drug discount program came under fire after a report from the Government Accountability Office.

July 11th 2015

Definition of "Value" in Cancer Care Varies

Laura Joszt, MA

The concept of value may be, and is, interpreted differently among healthcare stakeholders, and not only do cancer patients define value differently from policy makers, but also from other patients.

July 10th 2015

Largest-Ever Precision Medicine Oncology Trial Ready for Launch

Anita T. Shaffer

A landmark clinical trial that will channel patients into treatment arms based on molecular abnormalities rather than cancer type aims to simultaneously test the efficacy of more than 20 drugs.

July 10th 2015

Real-World and Phase 1 Safety Studies of Immuno-Oncology Agents in NSCLC and Glioblastoma

Surabhi Dangi-Garimella, PhD

Two posters summarized the safety of nivolumab in lung cancer and in glioblastoma, at the ASCO annual meeting.

July 9th 2015

JAMA Oncology Finds Gaps in End-of-Life Care as CMS Proposes Rule Change for Advance Care Planning

Mary K. Caffrey

A study of Kaiser Permanente cancer patients found that two-thirds of teen and young adult patients received aggressive care at the end of life. The special issue on the topic comes as CMS proposes paying doctors or nurses to discuss advanced care planning.

July 8th 2015

Dr Crystal S. Denlinger Calls for Personalized Care in Cancer Survivorship

AJMC Staff

As innovations in cancer care transform the disease into a chronic illness, the survivorship population encompasses more than early stage patients but survivors of long term metastatic disease as well, explains Crystal S. Denlinger, MD, Fox Chase Cancer Center in Philadelphia.

July 8th 2015

Researchers Identify 3 US Hot Spots With High Colorectal Cancer Death Rates

Laura Joszt, MA

While a better understanding has led to a drop in the colorectal cancer death rate by half, the progress made in the last few decades has not been equal across the United States, according to a study published in Cancer Epidemiology, Biomarkers & Prevention.

July 8th 2015

First Do No Harm: HER2-Positive Breast Cancer, Trastuzumab, and Cardiac Monitoring Guidelines: Part 2

Debra Madden

In part 1 of "First Do No Harm," Ms Madden noted important new research suggesting that the majority of patients with HER2+ breast cancer who are treated with the anti-HER2 agent trastuzumab do not receive sufficient cardiac monitoring. In part 2, she discusses the implications of this recent study for patients with this aggressive form of breast cancer and protective strategies against preventable harms of their treatment.

July 7th 2015

JAMA Study Says Screening Mammograms Result in Overdiagnosis

Surabhi Dangi-Garimella, PhD

The widespread use of screening mammography increases the probability of detecting smaller cancers without a decline in the detection of large cancers.

July 7th 2015

ACCC Launches ICLIO for Community Oncologists

AJMC Staff

ICLIO promises to guide oncologists in community care practices to navigate the growing field of immuno-oncology.

July 7th 2015

GAO Report: Congress Must End Incentives to Prescribe Expensive Cancer Drugs in 340B Program

Mary K. Caffrey

The report found that Medicare Part B spending per beneficiary in 340B hospitals was more than twice that of hospitals outside the program. Groups such as the Community Oncology Alliance have long warned that the 340B program, while essential, has grown beyond its original intent.

July 7th 2015

Melanoma Death Rates Expected to Continue to Increase

Laura Joszt, MA

Although the CDC expects death rates for most cancers to decrease by 2020, melanoma is the exception and new cases are expected to cost $1.6 billion in 2030.

July 6th 2015

Dr Bruce Feinberg Explains Why He Attends AJMC's Patient-Centered Oncology Care

AJMC Staff

Bruce Feinberg, DO, vice president and chief medical office at Cardinal Health Specialty Solutions, explains why he attends the sessions at Patient-Centered Oncology Care.

July 6th 2015

CDC Report Predicts Cancer a Continuing Burden on Healthcare Systems

Surabhi Dangi-Garimella, PhD

To evaluate the current status of cancer mortality following the initiation of HP2020, CDC scientists evaluated population trends and made projections on cancer deaths based on race and gender.

July 2nd 2015

First Do No Harm: HER2-Positive Breast Cancer, Trastuzumab, and Cardiac Monitoring Guidelines

Debra Madden

With a growing understanding of the risk of cardiotoxicity associated with cancer treatment, cardio-oncology has emerged as an important subspecialty, resulting in the establishment of cardio-oncology programs most often based at or in collaboration with comprehensive cancer centers.

July 2nd 2015

Overweight Colorectal Cancer Patients Outlive Those With the Lowest BMI, New Study Finds

Cate Douglass

Metastatic colorectal cancer patients with higher body mass index (BMI) outlived patients with the lowest BMI by an average of 2-and-a-half months, according to new data presented at the European Society for Medical Oncology 17th World Congress on Gastrointestinal Cancer 2015.

June 27th 2015

This Week in Managed Care: June 27, 2015

This week the Supreme Court ruled in favor of the government in King v. Burwell, preserving access to healthcare subsidies for millions of Americans, and the high cost of cancer drug was in the spotlight.

June 25th 2015

Biomarker Could Allow Early Detection and Reduce Mortality in Pancreatic Cancer

Surabhi Dangi-Garimella, PhD

Researchers at the MD Anderson Cancer Center have developed a blood test that can detect very early stages of pancreatic cancer before disease progression.

June 24th 2015

NICE Proposes a Symptom-Based Approach to Reduce Cancer Mortality

Surabhi Dangi-Garimella, PhD

NICE has updated and redesigned its guideline to support primary care physicians to recognize the signs and symptoms of 37 different cancers and refer people for the right tests faster.

June 24th 2015

Exploring the Placebo Response in Cancer Survivors

AJMC Staff

A clinical trial at the University of Alabama will be enrolling patients in the first-ever study of an open-label placebo in cancer.

June 23rd 2015

The Argument for More Selective Use of Breast Cancer Biomarker Testing

Laura Joszt, MA

A more selective use of biomarker testing for patients with breast cancer could save millions of dollars without compromising the care they receive, according to the results of a study published in The American Journal of Surgical Pathology.

June 22nd 2015

ASCO's Conceptual Value Framework Released: Tool for Shared Decision Making

Surabhi Dangi-Garimella, PhD

A framework that primarily considers clinical benefit, toxicity, and cost of new treatments was released today by ASCO. A presscast complementing the release described the framework as a tool for providers to discuss value of new treatments with patients, compared with the standard of care.

June 22nd 2015

Avoid Unnecessary Cancer Screening Following Venous Thromboembolism, Says NEJM Study

AJMC Staff

A study published in the New England Journal of Medicine says a CT scan following a first venous thromboebolism event may not benefit in detecting cancer.

June 22nd 2015

Oncogene Study Identifies Drug Resistance in BRAF/PTEN-Null Melanoma

AJMC Staff

Using mass-spectrometry—based phosphoproteomics, researchers at the Moffit Cancer Center have identified a mechanism by which BRAF/PTEN-null melanoma cells develop resistance to BRAF inhibitors.

June 19th 2015

Value-Based Calculator Estimates How Much Cancer Drugs Should Really Cost

Laura Joszt, MA

One of the most vocal physicians about the high prices of cancer drugs, Peter Bach, MD, MAPP, director of the Center for Health Policy and Outcomes at Memorial Sloan Kettering Cancer Center, recently led the effort to create a value-based calculator to determine the true worth of cancer drugs.

June 18th 2015

Use of Lumpectomy Among Early-Breast Cancer Patients on the Rise

Laura Joszt, MA

Despite the increased use of breast-conserving therapy among women with early-stage breast cancer, many women continue to undergo mastectomy, according to a study from researchers at the University of Texas MD Anderson Cancer Center in Houston published in JAMA Surgery.

June 18th 2015

Giving the Immune System a Boost in Cancer With DPP4 Inhibitors

Scientists at Institut Pasteur in France have repurposed DPP4 inhibitors, used to treat type 2 diabetes mellitus, to boost the body's immune response to tumors.

June 17th 2015

Smoking Boosts Cancer Mortality Rate: American Cancer Society Study

A report by the American Cancer Society, published in JAMA Internal Medicine, finds smoking significantly increases the risk of cancer-related death.

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