Oncology

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NSCLC | Image: Lung Cancer Foundation of America

Zongertinib Shows Durable Responses With No Interstitial Lung Disease in HER2-Mutated Advanced NSCLC

By Mary Caffrey
Brooke McCormick

April 28th 2025

Results could give patients with HER2-mutated non–small cell lung cancer (NSCLC) an oral therapy option.

Considering the life-threatening risk of TLS, the researchers underscored the importance of identifying patients at particular risk of the complication. | Image credit: mi_viri - stock.adobe.com

Optimized Strategies Needed for TLS Prevention, Intervention in SCLC

By AJMC Contributor

April 23rd 2025

Diabetes monitoring | Image credit: abidika - stock.adobe.com

New-Onset Type 2 Diabetes Linked to Higher Cancer Risk

By Pearl Steinzor

April 23rd 2025

Vitamin D | Image credit: Galina Zhigalova - stock.adobe.com

Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health

By Pearl Steinzor

April 23rd 2025

The study highlighted symptom patterns in the short-term preceding ED visits and unplanned hospitalizations using a previously validated natural language processing a pipeline. | Image credit: Tyler Olson - stock.adobe.com

Symptom Documentation Differences in Acute Cancer Care Suggest Sociodemographic Disparities

By Rose McNulty

April 22nd 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

More News

May 19th 2016

What We're Reading: Where Colon Cancer Strikes Affects Survival

AJMC Staff

Stories on the potential health savings if more people quit smoking, and Louisiana's failed attempt to put nursing homes in managed care.

May 18th 2016

Few Eligible Cancer Patients Received All Quality Measures That Improve Survival Rates

Laura Joszt, MA

Survival rates increase as more quality measures are incorporated into care, but only 13% of eligible patients with Stage IIIA non-small cell lung cancer actually receive all 4 measures.

May 17th 2016

Physical Activity Reduces Risk of 13 Types of Cancer

Brenna Diaz

High levels of physical activity are associated with lower rates of cancer, according to a new study published in JAMA Internal Medicine.

May 17th 2016

Breast Cancer Multigene Testing Trends and Impact on Chemotherapy Use

G. Thomas Ray, MBA Jeanne Mandelblatt, MD Laurel A. Habel, PhD Scott Ramsey, MD, PhD Lawrence H. Kushi, ScD Yan Li, MD Tracy A. Lieu, MD, MPH

A multigene test for breast cancer recurrence risk was used in a minority of eligible patients, yet was associated with a decrease in chemotherapy use.

May 16th 2016

ADHD Diagnosis May Actually Be a Rare Tumor, Say NIH Researchers

Surabhi Dangi-Garimella, PhD

A new study warns that symptoms associated with rare CNS tumors could lead to a misdiagnosis of attention deficit hyperactivity disorder among pediatric patients.

May 16th 2016

Choosing Between Nivolumab, Cabozantinib, and Newly Approved Lenvatinib Plus Everolimus in RCC

Surabhi Dangi-Garimella, PhD

The FDA has approved the combination of lenvatinib and everolimus for use in patients with renal cell carcinoma who have failed at least 1 anti-angiogenic treatment. The approval raises questions around the sequencing these agents when a patient fails on first-line care.

May 16th 2016

Defining "Value" in Oncology: Experts Weigh in on Frameworks

Rising costs in cancer care have fueled a national conversation on how to decide whether today’s new therapies are “worth it.” A supplement of Evidence-Based Oncology features interviews with those developing value frameworks and coverage of the Oncology Stakeholders Summit, which included patient advocacy, payers and pharmaceutical manufacturers.

May 15th 2016

Dr Lee Schwartzberg Discusses Results of Checkpoint Inhibitors in Breast Cancer

There is much excitement over the new checkpoint inhibitors, which have shown benefit across a variety of tumors. Right now, researchers are trying to define the subgroup of patients with breast cancer who might be most suited to checkpoint inhibitors, explained Lee Schwartzberg, MD, FACP, chief of Division of Hematology Oncology and professor of medicine at the University of Tennessee Health Science Center.

May 13th 2016

Progress Against Cancer on the Right Path: ACS Report

Surabhi Dangi-Garimella, PhD

According to a new report released by the American Cancer Society, prevention, early detection, and interventions have worked for controlling cancer-but only for those cancer types for which these tools are available.

May 13th 2016

Significant Toxicity of Mitoxantrone in Patients With Multiple Sclerosis: Cancer

Surabhi Dangi-Garimella, PhD

Researchers in Germany have discovered that mitoxantrone-used to treat aggressive, relapsing, or progressive multiple sclerosis-can increase the risk of leukemia and colorectal cancer in those being treated.

May 12th 2016

Nivolumab Approved by EC for Melanoma, Rejected by NICE for Lung Cancer

Surabhi Dangi-Garimella, PhD

The immunotherapy agent nivolumab was approved by the European Commission in combination with ipilimumab for the treatment of advanced melanoma, but rejected by the National Institute for Health and Care Excellence for use in patients with advanced lung cancer.

May 12th 2016

New Study Can Prevent Heart Damage in Patients Cured of Cancer

Priyam Vora

Cancer patients who receive a particular type of chemotherapy, called doxorubicin, run a risk of sustaining severe, lasting heart damage. But until now, there was no way of knowing who would experience this serious side effect.

May 12th 2016

Considerations for Designing "Value Calculators" for Oncology Therapies

Michael Dalzell

A review of the various value calculators that have emerged to measure the value of cancer therapies—these calculators reflect the interests of their developers and vary substantially in their intention, format, and usability.

May 12th 2016

Economists Refute Relation Between Size of Cancer Drug Vials and Healthcare Costs

Surabhi Dangi-Garimella, PhD

In a blogpost on Health Affairs, 2 economists have challenged the claim made by researchers that packaging expensive, patented chemotherapy drugs into multiple vial sizes could reduce wastage and in turn significantly reduce healthcare costs.

May 12th 2016

Dr John Thompson Discusses Screening and Diagnosis, Immunotherapy, and Biomarkers

While at the National Comprehensive Cancer Network’s 21st Annual Meeting, John A. Thompson, MD, co-director of the Melanoma Clinic at the Seattle Cancer Care Alliance, discussed screening and diagnosis of melanoma, immunotherapy, and biomarkers.

May 11th 2016

CancerCare Report Highlights Patient Struggles - Emotional, Financial, and Communication

Surabhi Dangi-Garimella, PhD

CancerCare's 2016 Patient Access and Engagement Report underscores barriers for patient access to care, as well as communication gaps with care providers, both of which have a significant impact on patient outcomes.

May 11th 2016

In Conversation With ASCO's Richard Schilsky

The American Society of Clinical Oncology (ASCO)’s Value Framework evaluates the clinical benefit, toxicity, and cost of new interventions compared with the standard of care. ASCO’s CMO, Richard Schilsky, MD, FACP, FASCO, explains their plans to make the framework useful for clinical decisions at the point of care.

May 10th 2016

NewLink's Pancreatic Cancer Vaccine Fails to Improve Survival in Phase 3

Surabhi Dangi-Garimella, PhD

Algenpantucel-L, an allogenic whole-cell immunotherapeutic vaccine being developed to destroy a patient’s pancreatic cancer cells, has failed to improve overall survival (OS).

May 10th 2016

Value in Cancer Care: An Economist's Perspective

Rena M. Conti, PhD

Measuring the quality of oncology care and associating it with reimbursement, and high drug prices remain important concerns of value-based outpatient cancer care. A healthcare economist reviews the current status and suggests a potential path forward.

May 9th 2016

Aetna to Cover Prosigna Gene Signature Assay for Breast Cancer

AJMC Staff

Nanostring Technologies has announced that its Prosigna Breast Cancer Gene Signature Assay has received a positive coverage decision from the commercial health plan Aetna.

May 9th 2016

Physician Participation Important as Patients Navigate Disease Information Online

Surabhi Dangi-Garimella, PhD

A new analysis of websites that provide information on pancreatic cancer, published in JAMA Surgery, has found that they overestimate the reading ability of the population and might even misguide them.

May 7th 2016

This Week in Managed Care: May 7, 2016

This week, the top stories in managed care included Express Scripts expressing a desire to partner with retail health clinics, a study that found oral cancer agents are being launched at much higher prices, and The American Journal of Managed Care's hepatitis C virus special issue was published online.

May 6th 2016

ICER's HTA Report for Multiple Myeloma: New Drugs Clinically Promising, Cost Effectiveness Unclear

Surabhi Dangi-Garimella, PhD

May 5th 2016

FDA Extends Authority Over E-Cigarettes, Receives ASCO's Praise

Surabhi Dangi-Garimella, PhD

With reports documenting the shockingly rising use of e-cigarettes by middle and high school children, the announcement today that the FDA will extend its regulatory authority to include e-cigarettes is welcome news.

May 5th 2016

Neutropenia and Avoiding Infection in Patients With Acute Myeloid Leukemia

Brenna Diaz

Patients with acute myeloid leukemia are extremely susceptible to infection, especially due to the prevalence of neutropenia.

May 5th 2016

Biomarker Could Help Determine Aggressiveness of Treatment in Head and Neck Cancer

Surabhi Dangi-Garimella, PhD

Scientists have discovered a new biomarker that could predict survival outcomes, and help establish the need for aggressive treatment, in patients with head and neck cancer.

May 5th 2016

Smokers Who Lie Cause Higher Health Costs for Everyone Else, Report Finds

Mary Caffrey

Smoking rates reported by insurers serving the ACA exchanges were consistently lower than findings from the CDC, suggesting that some are not being honest to avoid surcharges.

May 4th 2016

Dr Toby Campbell Explains Patient Understanding of Palliative Care Remains Limited

Patients and families can still have a limited understanding of palliative care, which may mean they have an open mind toward the suggestion, said Toby C. Campbell, MD, MSCI, associate professor of medicine, hematology-oncology at the University of Wisconsin School of Medicine and Public Health.

May 3rd 2016

Improved CRC Prognosis Goes Beyond the Success of Screening, Say Experts

Surabhi Dangi-Garimella, PhD

A new commentary in the New England Journal of Medicine has cautioned clinicians to tone down the perceived benefits of earlier screening in colorectal cancer.

May 3rd 2016

Arsenic in Private Wells Responsible for Surge in Bladder Cancer in New England

Surabhi Dangi-Garimella, PhD

A new study published in the Journal of the National Cancer Institute has identified the cause of the high rates of bladder cancer cases diagnosed in the New England region of the United States: arsenic in drinking water from private wells.

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