Oncology

Latest News

NSCLC | Image: Lung Cancer Foundation of America

Zongertinib Shows Durable Responses With No Interstitial Lung Disease in HER2-Mutated Advanced NSCLC

By Mary Caffrey
Brooke McCormick

April 28th 2025

Results could give patients with HER2-mutated non–small cell lung cancer (NSCLC) an oral therapy option.

Considering the life-threatening risk of TLS, the researchers underscored the importance of identifying patients at particular risk of the complication. | Image credit: mi_viri - stock.adobe.com

Optimized Strategies Needed for TLS Prevention, Intervention in SCLC

By AJMC Contributor

April 23rd 2025

Diabetes monitoring | Image credit: abidika - stock.adobe.com

New-Onset Type 2 Diabetes Linked to Higher Cancer Risk

By Pearl Steinzor

April 23rd 2025

Vitamin D | Image credit: Galina Zhigalova - stock.adobe.com

Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health

By Pearl Steinzor

April 23rd 2025

The study highlighted symptom patterns in the short-term preceding ED visits and unplanned hospitalizations using a previously validated natural language processing a pipeline. | Image credit: Tyler Olson - stock.adobe.com

Symptom Documentation Differences in Acute Cancer Care Suggest Sociodemographic Disparities

By Rose McNulty

April 22nd 2025

Join this expert panel to discuss precision medicine in NSCLC, current immunotherapies, and more.

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Join a panel of leaders as they discuss treatment for patients diagnosed with metastatic NSCLC without driver mutations

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September 29th 2014

Perjeta Improves Survival in HER2-Positive Breast Cancer Patients

The monoclonal antibody extended survival by nearly 16 months compared to those in the control cohort.

September 29th 2014

ESMO 2014: Nivolumab Promise in Melanoma

Results from the CheckMate-037 trial showed a significant increase in duration of response in patients with advanced melanoma administered nivolumab as second- or third-line therapy

September 26th 2014

Hypercalcaemia as an Early Cancer Biomarker

A study published in the British Journal of Cancer discovered a correlation between hypercalcaemia and the risk of cancer, specifically in males.

September 26th 2014

ESMO Congress: Researchers Identify Barriers to Drug Access

The researchers identified discrepancies across the globe in patient access to life-saving cures for cancer.

September 26th 2014

A New Drug Delivery Vehicle: Anthrax Bacteria

Having delivered antibody mimics to cancer cells in vitro, the research group at MIT that conducted the research is now working on evaluating the technique in tumors grown in mice.

September 25th 2014

Lung Infections May Hamper Efficacy of FDG-PET

A new retrospective study published in JAMA identified that tuberculosis and certain fungal infections in the lungs could hamper the efficient detection of lung cancer by FDG-PET imaging.

September 25th 2014

Treating Late-Stage Lung Cancer Not Cost-Effective: JTO Study

A prospective study published in The Journal of Thoracic Oncology found that the average cost to screen high-risk individuals for developing lung cancer with low-dose computed tomography plus the average cost of curative intent treatment, like surgery, is lower than the average cost to treat advanced stage lung cancer, which quite rarely results in a cure.

September 24th 2014

Proton Radiation-Yea or Nay?

Controversy over the value of proton beam radiation continues to harass clinicians as the therapy emerges to be extremely useful in some, but not all, cancers. Additionally, payers sometimes refuse to cover treatment costs due to lack of evidence of efficacy.

September 24th 2014

NCI's New Approach With The Exceptional Responder Initiative

With the aim of understanding why some patients respond better to a particular drug, NCI has launched the Exceptional Responders Initiative, to generate molecular profiles of tumors that respond well to a particular treatment.

September 24th 2014

PAD2 Overexpression May Promote Skin Cancer

Research published this month in the journal Cancer Research, found that increased expression of the enzyme PAD2 in young mice could lead to skin tumors that could progress to invasive squamous cell carcinoma.

September 23rd 2014

Folowing AACR, ASCO Supports FDA's Guidance for LDTs

The ASCO statement corroborates the need for regulation of laboratory-developed tests, which are increasingly being used to guide personalized treatment in oncology as well as other therapeutic areas.

September 23rd 2014

Should We Pay Doctors Less for Colonoscopy?

Shivan J. Mehta, MD, MBA Scott Manaker, MD, PhD

Due to existing payment structures and practice patterns for colonoscopy, reducing endoscopist reimbursement may diminish access to and quality of colorectal cancer screening.

September 23rd 2014

Updated International Consensus Guidelines for Advanced Breast Cancer Published

The guidelines have been published in 2 journals: Breast and Annals of Oncology.

September 22nd 2014

Amgen's Blinatumomab Get's Breakthrough Status for ALL

The drug is the first in it's class - an antibody designed to engage 2 different targets simultaneously.

September 22nd 2014

New Graphene Biosensor to Detect Cancer Biomarkers

The biosensor, which can detect the oxidative stress marker 8-hydroxydeoxyguanosine, is 5-times more sensitive than the ELISA test that is commonly used to identify biomarkers.

September 19th 2014

Gilead's Zydelig Receives EU Nod for CLL and FL

The approval in CLL is supported primarily by data from a randomized, placebo-controlled phase 3 trial in combination with rituximab in 220 patients with relapsed CLL who were not able to tolerate standard chemotherapy. The approval in FL, is supported by data from a single-arm phase 2 study (Study 101-09) of Zydelig monotherapy in 125 iNHL patients refractory to rituximab and alkylating-agent-containing chemotherapy.

September 19th 2014

Microbubbles: New Carrier for Chemotherapy Delivery

The study, conducted in pancreatic cancer patients in Norway, was presented at the annual meeting of the International Contrast Ultrasound Society in Chicago.

September 19th 2014

Recurrence of Breast Cancer Years After the Initial Tumor

Marj P. Zimmerman, MS, BSPharm Stanton R. Mehr

September 19th 2014

Cancer Trials Face a Shortage of Teen, Young Adult Enrollees

Surabhi Dangi-Garimella, PhD

September 19th 2014

Draft Statement: Evidence Connecting Diet to Colorectal, Breast Cancer Stronger Than Links to Lung, Prostate

Mary K. Caffrey

September 19th 2014

First PD-1 Inhibitor Approved for Melanoma

Surabhi Dangi-Garimella, PhD

September 19th 2014

AACR Seeks FDA Oversight on LDTs

Surabhi Dangi-Garimella, PhD

September 19th 2014

Immunotherapy Trials Offering Promise in Hard-to-Treat Pancreatic Cancer

Mary Caffrey

September 19th 2014

Patient-Contributed Tumor Genetics Data: A Pathway to Better Drug Development

Yair Benita, PhD Barbara Marino, PhD Aman Bhandari, PhD Roni Zeiger, MD Sachin H. Jain, MD, MBA

September 19th 2014

Moving Beyond BRCA Mutations in Familial Breast Cancer

Surabhi Dangi-Garimella, PhD

September 19th 2014

Breast Cancer Survivorship Programs: More Than a Treatment

Marj P. Zimmerman, MS, BSPharm Stanton R. Mehr

September 19th 2014

Avastin: First Molecule in Nearly a Decade for Metastatic Cervical Cancer

Surabhi Dangi-Garimella, PhD

September 19th 2014

FDA Oversight of Laboratory Developed Tests Essential for Patient Health and Safety

Rep. Louise M. Slaughter, MPH

September 19th 2014

Thyroid Cancer: Increased Incidence or Improved Diagnosis?

Sejal Saraiya, PharmD

September 19th 2014

Oncology Medical Home: Improved Quality and Cost of Care

Surabhi Dangi-Garimella, PhD

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