Research documentation is a critical aspect of running a clinical trial. Key patient information such as informed consent, adverse events (AEs), concomitant medications, and medical and surgical histories are collected and used to determine patient safety and efficacy as the trial proceeds. Ultimately, the sponsor may make decisions—ranging from modifying the dose of the investigational drug to closing the study due to AEs—based on the data collected.
Ten percent of patients abandon newly initiated oral oncolytics at the pharmacy. Patients facing higher cost sharing or increased concurrent prescription activity have a higher abandonment rate.
Increasing LACE+ index score is a significant predictor of greater risk of unplanned readmission, emergency department visits, and reoperation after gynecologic surgery.
This study describes the small number of individuals responsible for larger shares of healthcare cost persistently over a 3-year period.
On average, the health coach intervention cost $483 per participant per year. There was no evidence that the coaching intervention saved money at 1 year.
Medicare claims analyses offer insight into how proposed policy changes would affect out-of-pocket prescription costs for Part D beneficiaries requiring specialty drugs.
Implementation of a point-of-care case management team consisting of a nurse, social worker, pharmacist, and health navigators reduced readmissions and associated costs.
This commentary proposes a bundled measure of unplanned post-hospital care to better assess the true impact of readmissions reductions programs and to avoid unintended consequences.
Home telemonitoring represents a promising approach for the management of respiratory conditions and supports early identification of deteriorations in patient condition and symptoms control.
Oral anticancer medications are frequently used to treat patients with cancer. We found significant time and energy burdens for clinic staff and patients in obtaining these drugs.
A nurse following treatment alogrithms with prescription authority in a primary care setting markedly improved diabetes outcomes; 47% met ADA A1C, LDL-C, and BP goals.
This pharmacist-led, patient-directed intervention demonstrated a reduction in opioid dispensings in the 90 days following hip replacement but not knee replacement.
The authors evaluated a new "big data" analytic predictive platform that quickly and accurately analyzes large data sets to identify populations at risk of developing conditions such as metabolic syndrome.
Hospitals that used trained financial navigators were able to provide financial assistance for their patients with cancer, providing access to care that would otherwise be unaffordable.
This study presents an integrated, exploratory assessment of physical activity, patient activation, health-related quality of life, and clinical outcomes among older adults with type 2 diabetes (T2D) using survey, wellness, and claims data.
A multivariable sensitivity analysis conducted on a pharmacy follow-up program of high-risk patients demonstrated cost savings to hospitals in 98.3% of head-to-head trials across 1000 hypothetical hospitals.
Accountable care organizations will be more successful in taking on accountability for patient outcomes when market and firm organization get a balanced treatment.
Use of Toyota production system methods as part of a nosocomial MRSA prevention initiative on a surgical unit improved quality of care in other areas.