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Health of Medicare Advantage Plan Enrollees at 1 Year After Hurricane KatrinaAt 1 year after Hurricane Katrina, the health burden of enrollees increased significantly more versus a comparison group. Emergency department visits and hospitalizations remained elevated.
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Value of Improved Lipid Control in Patients at High Risk for Adverse Cardiac EventsReducing lipid levels in high-risk patients can significantly reduce disease burden and, depending on final negotiated prices, PCSK9 inhibitors can make an economic contribution to this goal.
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Cost-Effectiveness of DPP-4 Inhibitor and SGLT2 Inhibitor Combination Therapy for Type 2 DiabetesThis study evaluates the long-term cost-effectiveness of treatment involving combination therapy with dipeptidyl peptidase 4 (DPP-4) inhibitors and sodium-glucose cotransporter 2 (SGLT2) inhibitors compared with an alternative with sulfonyureas prior to insulin initiation on a background of metformin.
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Real-World Economic Value of a 21-Gene Assay in Early-Stage Breast CancerUniversal gene expression profiling of patients with stage II breast cancer resulted in outpatient savings of $11,000 (inclusive of testing costs) within 6 months of initiation of medical therapy.
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Excess Hospitalization Days in an Academic Medical Center: Perceptions of Hospitalists and Discharge PlannersWe assessed the frequency of and reasons for medically unnecessary hospital days, which affect patients, payers, hospitals, and healthcare providers.
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Patient-Centered Oncology Care: Impact on Utilization, Patient Experiences, and QualityPractices implementing a patient-centered oncology care pilot had improved quality, but utilization and patient experiences did not differ from comparison practices.
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Economic Implications of Weight Change in Patients With Type 2 Diabetes MellitusModest weight loss (>3%) among metformin-treated patients with type 2 diabetes mellitus was associated with decreased costs, lower resource utilization, and lower rates of treatment discontinuation.
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Can a Nationwide Media Campaign Affect Antibiotic Use?A nationwide media campaign aimed at parents was associated with reductions in the use of antibiotics for pediatric upper respiratory infections, otitis media, and pharyngitis.
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Financial Incentives and Physician Commitment to Guideline-Recommended Hypertension ManagementFinancial incentives may not be strong enough to influence physician goal commitment to guideline-recommended hypertension care when providers attribute performance to forces beyond their control.
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Nurse-Run, Telephone-Based Outreach to Improve Lipids in People With DiabetesNurses can improve lipid control in people with diabetes in a primarily indigent population through telephone care using moderately complex algorithms. Telephone-based outreach may decrease resource utilization.
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Comparative Effectiveness of Early Natalizumab Treatment in JC Virus-Negative Relapsing-Remitting Multiple SclerosisWe estimated the long-term risks and benefits of disease modifying therapies. Benefits were favored by natalizumab with minimal increased risks in the negative anti-JC virus population.
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Applying Weighting Methodologies to a Commercial Database to Project US Census Demographic DataThis study tests the feasibility of projecting commercial insurance demographic information to the US Census population, and creating the framework for a simple weighting scheme.
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Improving Influenza Immunization in Pregnant Women and Healthcare WorkersInfluenza vaccination rates in pregnant women and healthcare workers were increased with standing orders, vaccine advocates, and educational activities on influenza immunization.
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Prolonged Cessation of Chronic Opioid Analgesic Therapy: A Multidisciplinary InterventionThis article evaluates the immediate and long-term efficacy of a group multidisciplinary program for chronic opioid analgesic therapy cessation in the setting of chronic, noncancer pain.
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Budget Impact Analysis of Biosimilar Natalizumab in the USProjected savings from biosimilar natalizumab were $452,611 over 3 years, driven by decreased drug acquisition costs and a utilization shift from reference to biosimilar natalizumab.
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Use of Postacute Care After Discharge in Urban and Rural HospitalsRural patients receive less postacute care after hospital discharge than urban patients, especially after elective joint replacement-a condition selected for bundled payments.
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Primary Care Diabetes Bundle Management: 3-Year Outcomes for Microvascular and Macrovascular EventsUsing a system for primary care management of patients with diabetes may reduce the risk of myocardial infarction, stroke, and retinopathy over a 3-year period.
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Can a Nationwide Media Campaign Affect Antibiotic Use?A nationwide media campaign aimed at parents was associated with reductions in the use of antibiotics for pediatric upper respiratory infections, otitis media, and pharyngitis.
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Understanding and Improving Value Frameworks With Real-World Patient OutcomesNew value frameworks should incorporate real-world evidence that reflects patient treatment behavior, adherence to medication, and equity concerns arising from disparities in care.
