The AJMC® Parkinson Disease compendium is a comprehensive resource for clinical news and expert insights for progressive nervous system disorder, which affects movement and often includes tremors.
Motor Symptoms May Occur 3 Years Before Parkinson Disease Diagnosis, Study Says
January 20th 2023Trouble with balance and holding objects above one's head were just a few of the problems reported by patients 3 years before they received a formal Parkinson disease diagnosis, according to a recent study.
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Improved Patient-Reported Outcomes Shown With Mediterranean Diet in Parkinson Disease
December 12th 2022Patients with Parkinson disease who adhered to Mediterranean (MEDI) and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets were associated with fewer patient-reported symptoms over time, in which the MIND diet showed greater reductions in symptom severity compared with MEDI.
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Assessing Frequency of Orthostatic Hypotension in Patients With Parkinson Disease
December 7th 2022Frequency of orthostatic hypotension among Ethiopian patients with Parkinson disease (PD) was shown to be higher than that among healthy controls, with a higher proportion of constipation, urinary urgency, and nocturia symptoms reported in those with PD.
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Long-term Pioglitazone Use May Reduce Risk of Parkinson Disease in Patients With Diabetes
November 25th 2022Findings of a meta-analysis show that pioglitazone use with a dose duration greater than 438 days was associated with a significantly reduced risk of Parkinson disease in patients with diabetes.
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Incidence and Severity of Neurologic Diseases Worsening Due to Air Pollution, Climate Change
November 16th 2022Climate change and exposure to airborne pollutants was associated with incidence and exacerbation of several neurologic diseases, including migraine, dementia, and Parkinson disease.
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Simvastatin Ineffective as Disease-Modifying Therapy for Intermediate Parkinson Disease
November 10th 2022Patients with intermediate and mild Parkinson disease, defined by a Hoehn & Yahr stage of 3 or less, experienced an additional deterioration in motor function with simvastatin compared with placebo while not taking medication at 24 months.
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Examining Risk Factors, Prodromal Features of Parkinson Disease
November 9th 2022Several known risk factors and prodromal features were associated with Parkinson disease, including traumatic brain injury and alcohol misuse, along with other comorbidities such as skin and gastrointestinal disorders.
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Intermediate Parkinson Disease Associated With Significant Clinical, Economic Burden
November 2nd 2022A poster presented at Academy of Managed Care Pharmacy Nexus 2022 shows that patients with intermediate Parkinson disease place a significant resource burden on the US health care system in regard to treatment, emergency department visits, and admissions to rehabilitation centers.
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Evaluating Impact of COVID-19 Pandemic on Informal Caregivers of Patients With Parkinson Disease
October 24th 2022Informal caregivers of people with Parkinson disease residing in the United Kingdom discussed challenges faced in providing care during the COVID-19 pandemic, which included risk of infection, lack of access to care, and the impact of lockdown on engaging in activities of daily living.
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Cataract Surgery More Common in Patients With Parkinson Disease Prior to Diagnosis
October 18th 2022Patients with Parkinson disease (PD) from Finland reported a higher incidence rate of cataract surgeries prior to PD diagnosis vs those without the condition, potentially due to other eye diseases and prodromal symptoms of PD.
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Community-Based Cycling Program Shows Positive Impact on Symptom Management in Parkinson Disease
October 3rd 2022Location, cost, and transportation were cited as important factors regarding adherence and satisfaction with community-based exercise programs among patients with Parkinson disease.
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Square-Stepping Exercise Linked With Improved Executive Functioning in Parkinson Disease
September 28th 2022Adherence to 8-week square-stepping exercise training among patients with Parkinson disease was associated with significant improvement of executive functioning, as well as cognitive functioning for those with mild cognitive impairment.
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Pramipexole, Citalopram Effective Therapies for Depression in Parkinson Disease
September 16th 2022Patients with Parkinson disease demonstrated significant reduction in depressive symptoms with citalopram and pramipexole, with pramipexole showing slightly more benefit in improving quality of life.
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Elevated Incidence of Antipsychotic Use Found Prior to Parkinson Disease Diagnosis
September 10th 2022Initiation of antipsychotics was nearly 3 times more common in patients with Parkinson disease vs controls, with the incidence rate found to increase approximately 4 years prior to PD diagnosis.
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COVID-19–Related Impact on Physical, Cognitive Symptoms in PD Greater in Lower-Income Countries
September 7th 2022Significant worsening of physical and mental symptoms of Parkinson disease was shown in a meta-analysis of diverse patients during the COVID-19 pandemic, with those of lower-income countries shown to be exceptionally vulnerable.
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Sleep Abnormalities Linked With Increased PD Risk in Older Men
September 3rd 2022Older adults who reported longer total sleep time, lower rapid eye movement (REM) sleep percentage, and higher minimum oxygen saturations during REM sleep had an increased risk of developing Parkinson disease (PD).
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Healthy Diet, Exercise Linked With Reduced Mortality Risk in Parkinson Disease
August 22nd 2022Patients with Parkinson disease who adhered to a healthy diet pattern and active lifestyle had a lower rate of all-cause mortality than those reporting poor diet quality and lack of physical activity.
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Kidney Function Linked With Parkinson Disease Risk in Patients With T2D
August 16th 2022Korean patients with type 2 diabetes (T2D) who had reduced levels of estimated glomerular filtration rate and/or proteinuria, 2 hallmarks of diabetic kidney disease, had a greater risk of developing Parkinson disease.
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